Results from the Odyssey trial will be presented at this year’s Conference on Retroviruses and Opportunistic Infections in Boston, USA.
Pharmacokinetics of dolutegravir 5mg dispersible tablets in children weighing 6 to <20kg dosed using WHO weight bands
Authors: Waalewijn H, Bollen PDJ, Moore C, Kekitiinwa A, et al. The ODYSSEY Trail TeamPublished in: Oral Presentation at 10th IAS Conference, July, 21-24th 2019 Download
Authors: Turner B, Ford D, Moore C, Gibb D, Turkova A, White I, and ODYSSEY trial teamPublished in: Oral Presentation atInternational Society for Clinical Biostatics; July 16th 2019 Download
We are pleased to announce that recruitment to the main trial has now completed. We have recruited slightly more than the total target of 700 participants: 312 recruited into ODYSSEY A (naïve to HIV treatment) and 396 into ODYSSEY B (starting second line HIV treatment). A huge thank you to all involved in achieving this milestone!
Recruitment of children 3-<14kg has commenced at sites taking part in the pharmacokinetic substudy, and will continue until 60 children 3-<14kg have been recruited.
ODYSSEY B, which compares dolutegravir versus standard-of-care drugs in HIV-infected children who are starting second-line treatment, has completed recruitment ahead of target. 395 children have enrolled, mostly in Africa. Enrollment into ODYSSEY A for children starting treatment for the first time continues.
With more than 350 patients randomized into the trial, ODYSSEY has reached 50% of its recruitment target. Congratulations to the ODYSSEY team!
We are happy to announce that the first patient was enrolled in the ODYSSEY study by the team in Zimbabwe. We encourage all the sites to follow.